1. An electrophilic substitution reaction on benzene does not always result in monosubstitution. 2. In electrophilic substitution in aliphatic compounds, an electrophile displaces a functional group. 3. The alpha carbon then undergoes electrophilic substitution with bromine. 4. For instance, the page dealing with electrophilic substitution could benefit from showing a mechanism. 5. Indole undergoes electrophilic substitution , mainly at position 3 ( see diagram in right margin ). 6. However, electrophilic substitution is relatively facile at the 5-position, including nitration and halogenation. 7. A noteworthy exception occurs when electrophilic substitution is carried out in conditions sufficiently acidic to exhaustively protonate C3. 8. Imine generation is repeated a third time and the reaction concludes with a second electrophilic substitution to the other aromat. 9. This allows for strictosidine s formation under the subsequent ring closure via electrophilic substitution , as shown in the adjacent image. 10. Explain the Electrophilic substitution reaction in Durene . Preceding contribs ) 2005-07-12 23 : 55 : 45 CDT
Mobile